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Tirzepatide's dual mechanism may cause slightly higher rates of gastrointestinal side effects, but it remains a safe option for most patients

Many people prefer evening injections after dinner because side effects (particularly nausea) are often worse in the hours following injection

[18] [19] The mechanism of action involves binding to receptors in the pancreas, brain, and gastrointestinal tract, which influences insulin secretion and appetite regulation

Proprietary surveys indicate enthusiasm for weight loss drugs among consumers and in the primary care setting, especially if access improves

Since GLP-1 RAs are able to reduce appetite and induce satiety and early post-prandial fullness, their use is associated with a significant weight loss secondary to a reduced caloric intake [24]