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Clinical trials showed an average weight loss of 11.2% over 16 months at the highest dose
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The cyclic GMPAMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, a key mediator of inflammation, has emerged as a critical mechanism for sensing and regulating the cellular response toward microbial and host-derived DNAs [129]
Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: The STEP 4 randomized clinical trial
