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Description
Tirzepatide has an amphiphilic nature, meaning part of the molecule is water-loving and part is water-fearing (the C20 fatty acid chain)

The Basics GLP-1 meds slow stomach emptying

Clinically, GLP-1RAs like semaglutide induce sweet hyposensitivity and reduce preference for hyperpalatable foods, an effect mediated by changes in endogenous GLP-1 secretion and synaptic plasticity in reward circuits (166)

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10.1038/s41598-021-88612-x 37 KazankovK.JrgensenS
