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As global obesity rates continue to climb, so does the demand for effective, long-term pharmacological solutions beyond lifestyle interventions
It's important to note that GLP-1 medications themselves have a low risk of causing hypoglycaemia unless combined with insulin or sulphonylureas, where blood glucose monitoring is particularly important
Other risk factors for B12 deficiency that may coexist include proton pump inhibitor or H2-antagonist use, vegan/vegetarian diets, previous bariatric surgery, pernicious anaemia, and other malabsorptive conditions
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4 The mechanisms and pathways of GLP-1 regulating blood glucose 4.1 Promotion of insulin synthesis Transcription factors regulate gene expression by binding to specific enhancer sequences
