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Retatrutide includes GLP-1 activity, but it is not only a GLP-1 drug

Upon binding to their respective receptors on pancreatic beta cells, GIP and GLP-1 enhance insulin secretion in a glucose-dependent manner

GLP-1 medications are not suitable for everyone

Li: GLP-1s do not affect everyone the same way

is supported by the American Heart AssociationBristol Myers Squibb Foundation through the Winn Diversity in Clinical Trials Clinical Investigator Leadership Award, and by the National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Physician-Scientist Career Development Award, Grant Number K12DK133995 (David Maahs, Linda DiMeglio, Multi-Center Program Directors)