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GLP-1R activation and multifunctional effects GLP-1 has its main effects through the activation of GLP-1R which belongs to the family of G-protein coupled receptors
Protein kinase C and fatty acid transport protein 4 (FATP4) [144] play an important role in the increase of GLP-1 secretion and improvement in glycemic tolerance caused by oleic acid (OA), both in vivo and in vitro [145]
Additionally, the findings may have limited generalizability because the Mass General Brigham population is older, less likely to have a BMI of 25 or higher, less representative of Black and Latino individuals, and less likely to have public insurance
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