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It has been suggested that the vagus nerve mediates the aversive effects of GLP-1, as ip injection of exendin-4 induces CFA in vagotomised but not sham-operated rats [151]

Mller, Alberto Cebrian Serrano, Thomas Gudermann, Noushafarin Khajavi Unimolecular triagonist peptides combining glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon activity represent a new frontier in the treatment of obesity and type 2 diabetes

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