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Published online May 2024
For example, some studies reported an average weight loss of 5.4% to 8.1% of starting body weight with Contrave, versus 1.3% to 4.9% with placebo
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Studies indicate alarming discontinuation rates 53.6% of patients stop GLP-1 therapy within one year, and 72.2% discontinue within two years
Though the trial was powered to only detect non-inferiority, the observed (non-significant) hazard ratio for semaglutide vs
