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Semaglutide : Approved since 2017 with 7+ years post-marketing data

In a rat model of subtotal nephrectomy, which mimics CKD, 7 weeks of twice-daily liraglutide treatment attenuates Ager expression in the kidney

These findings suggest potential neuroprotective benefits of semaglutide, especially regarding cognitive health, and call for further research to validate its use in treating cognitive deficits and substance misuse in patients with T2DM (87)

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General anesthesia inherently increases the risk of aspiration because of a combination of factors, including diminished airway protective reflexes, decreased lower esophageal sphincter tone, and the use of positive pressure ventilation