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Table of Contents How GLP-1 therapies interact with the gut Microbiome shifts and metabolic outcomes Inflammation, gut integrity, and insulin resistance Clinical implications and future research directions How GLP-1 Therapies Interact With the Gut Environment GLP-1 is not just a pancreatic hormone

Stay well-hydrated, consume adequate fiber, and eat smaller, frequent meals to manage combined GI effects

table 2)

Avoid greasy or overly sweet foods, which trigger nausea more readily

Additionally, our reliance on all-cause mortality rather than NEN-specific endpoints, while methodologically sound, may obscure precise mechanisms of benefit