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Multiple randomized controlled trials including the SUSTAIN series demonstrate that GLP-1 therapy improves HOMA-IR (a measure of insulin resistance) and fasting insulin levels independent of weight loss alone

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Quick Answer: GLP-1 receptor agonists do not directly cause increased urination, as they are not diuretics and polyuria is not a recognised adverse effect

To view or add a comment, sign in In a recent Pharmacy Times interview, I discussed RECLASS-T1D findings showing ~2.2% (1 in 46) of adults initially labeled prediabetes or type 2 diabetes were later reclassified as type 1 diabetes