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Using GLP-1 drugs for weight loss is considered safe but can come with a loss of lean muscle mass

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The framework prioritised semaglutide and tirzepatide as first-line treatments, based on evidence of 15% weight loss and benefits in complications such as cardiovascular disease and sleep apnoea

Taking ibuprofen while on semaglutide requires careful consideration because both medications can affect your digestive system

Learn which drugs protect your heart and kidneys and why your doctor should know about them.