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Tremors in Hands : A subtle but constant trembling in the hands is a classic symptom that often goes unnoticed

Thus, incubating human and rodent islets under high glucose conditions results in increased expression of PC1/3 and increased secretion of GLP-1 (101, 108110), while exposure of -cells to the proinflammatory cytokine, interleukin-6, also increased GLP-1 secretion (112)

Graeme Bell and others went on to clone mammalian versions of preproglucagon: a gene that encodes a large protein precursor, which is cleaved to produce glucagon and two glucagon-like peptides (GLP-1 and -2)

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