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They can do this by eating less and being more active

Aim for adequate fluid intake throughout the day, increasing if experiencing nausea, vomiting, or diarrhoea

more frequent at higher concentrations Diarrhea common during early exposure or escalation periods Constipation reported alongside other GI disturbances Increased heart rate average increase of roughly 2 to 3 beats per minute Administration site reactions ranging from mild redness to localized nodules Gallbladder disorders including gallstones, especially at higher concentrations and longer durations Acute kidney injury primarily linked to volume contraction from GI fluid loss Pancreatitis a labeled risk, though large meta-analyses show no significant increase vs

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The NHS advises most adults need 69 hours of sleep per night