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Overall architecture In the cryo-EM structure of the GLP-2GLP-2RG s complex, most of the receptor core, G protein subunits and the first 31 amino acids of GLP-2 were observed with high-resolution features, thereby allowing for accurate modeling of side-chain rotamers (Fig

designed degradation-resistant GLP-2 analog dimer, GLP-2, which increased total gut weight, length, and villus height as well as crypt depth and crypt cell proliferation in DSS-induced mouse model of colitis (Gu et al

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Vomiting, while less common than nausea, may occur in some patients and can occasionally be severe enough to warrant treatment discontinuation