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If you find that dietary changes and hydration arent enough to manage constipation, consider over-the-counter remedies after consulting with your healthcare provider

In a recent clinical trial that diagnosed SIBO using both small intestine aspirate contents and stool sample cultures, the small intestinal flora of PPI-treated and non-PPI-treated individuals was not significantly different (Weitsman et al., 2022)

2026 Jan 2;16:1702448

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A fourth pillar, agents with cardiovascular and kidney benefit, has recently been added [5]
