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The expression of ELT-3::mCherry and PQM-1::mCherry in DTC showed no difference between WT worms and glp-1 mutants (Fig

However, these studies are observational, not randomized trials, so we cannot yet interpret the findings as proof of a cancer risk reduction. The review also addressed the question of whether GLP-1s reduce cancer risk because they cause weight loss and improved metabolism, or because they have a direct anti-cancer effect

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