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If you already have mood disorders, talk to your doctor before starting GLP-1 meds

Starting FDAApproved weight management medications

These agonists bind to GLP-1R and stimulate its pharmacological effects, increasing glucose-dependent insulin release from pancreatic cells, suppressing the release of glucagon from pancreatic cells, delaying the rate of gastric emptying, and slowing the glucose absorption rate

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The STEP-1 trial reported approximately 15% average body weight reduction with semaglutide 2.4mg over 68 weeks
