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Phase 2 trials reported 24.2% average bodyweight loss at highest doses over 48 weeks (NEJM)

Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: A randomised, double-blind, active-comparator, non-inferiority clinical trial

The trajectory of weight gain in this study was relatively smaller than STEP 1, possibly due to the smaller amount of weight loss in this group but also due to continued lifestyle intervention support after medical withdrawal as mentioned above [51]

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Abstract Multiple sclerosis (MS) is a chronic, progressive autoimmune disease modulated by autoantibodies that inflame and destroy the myelin sheath encasing neuronal axons, impairing proper axonal conduction and function