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Salas-Whalen described her framework for protecting muscle and metabolism: what she calls the GPS prescription

Wettergren A, Schjoldager B, Mortensen PE, Myhre J, Christiansen J, Holst JJ (1993)

Conclusions This multicenter emulated target trial showed that SGLT2i use was associated with a lower risk of incident PsA compared with GLP-1 RA use

The introduction of an oral tablet may seem incremental compared to the excitement that greeted the original injectables, but I believe it represents a substantial advance for the category

Conclusion GLP-1 receptor agonists represent a paradigm shift in obesity and diabetes treatment, demonstrating unprecedented efficacy across multiple health domains ^1^36