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2024 doi: 10.2337/dci24-0003

Inflammatory markers like C-reactive protein (CRP) decline significantly

The factors contributing to bone impairment in individuals with PWS are not fully understood, but possible explanations include loss of function of genes in the q11-q13 region of the paternal copy of chromosome 15, reduced production of sex hormones during puberty, as well as a relative GHD during childhood and adolescence (79)

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