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But for researchers interested in the cutting edge of anti-aging and metabolic optimization , it represents an intriguing complementary approach that works through entirely different mechanisms than incretin-based therapies

For comparison, the SURMOUNT-1 trial for tirzepatide showed an average of 20.9% weight loss at the highest dose over 72 weeks

A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American Heart Association