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Eating regular mealsrather than skipping themcan also help regulate appetite and reduce cravings over time
However, BBRs translational applications face biopharmaceutical challenges, including poor intestinal absorption ( 50% in obesity across murine and human models [170,171,172,173]

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(ii) current contraceptive method
However, the topiramate group demonstrated a reduction in visceral adiposity and lower very-low-density lipoprotein cholesterol (VLDL-C) levels, with no adverse effects [91]