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The exploration of GLP-1s mechanisms also present opportunities for novel therapeutic developments
The increase in cAMP levels in -cells is a consequence of GLP-1R activation in these cells, which in turn enhances the secretion of growth inhibitory hormone through signaling pathways such as PKA and Calcium/Calmodulin-dependent protein kinase (Strowski et al., 2000
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Nutritional approaches to enhance GLP-1 analogue therapy in obesity: A narrative review
See also Supplemental Figure 3 and Supplemental Table 2
