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Following intravenous injection (0.05 mg/kg, n=5), plasma concentrations of liraglutide decreased monoexponentially with an average half-life of 3.67 h
Similarly, the specific blocking of Gq signalling with YM254890 or transient receptor potential melastatin 5 (TRPM5) with triphenylphosphine oxide (TPPO) suppressed the triagonist-induced enhancement of GSIS
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