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Much of the field is now being built on multi-mechanism approaches: tirzepatide combining GLP-1 and GIP, retatrutide adding glucagon to that mix, and cagrilintide plus semaglutide taking yet another route to polyagonism
The iodinated protein was assembled by increasing concentrations of phase B (Acetonitrile + 0.1% TFA) and tested for competitive binding ability

10.1016/j.mcna.2023.06.001 34 LangerR
