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Any significant weight loss, regardless of method, results in some lean mass loss

Treatment starts with 0.25 mg once weekly for 4 weeks as an initiation dose (not for glycaemic control), then increases to 0.5 mg once weekly

For instance, native GLP-1 infusion acutely reduced food intake in individuals without ( While GLP-1R agonism effectively reduces body weight in patients, there is a persistent need for greater efficacy of weight loss and comorbidity resolution

Always have fast-acting carbohydrates, like glucose tablets or juice, on hand to quickly address low blood sugar episodes as advised by your doctor