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Semaglutide is a lab-made version of a hormone called GLP-1 which your body makes naturally and helps control blood sugar and appetite

Its involvement at the intersection of metabolic regulation, stress responsiveness, and reproductive endocrinology positions it as a candidate for conditions in which these domains converge, such as menopause-associated metabolic dysfunction or stress-related eating disorders

As we and others have previously shown benefit for semaglutide and other GLP-1RA medications in AD, our results support the GLP-1 receptor as a target for dementia prevention

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Author contributions LF: Conceptualization, Methodology, Project administration, Writing original draft