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However, you should be aware of potential side effects , including nausea, diarrhea, and decreased appetitecommon across many diabetes medications, including Ozempic and Wegovy

In the SURMOUNT-1 trial, tirzepatide produced average weight reductions of 15.0%, 19.5%, and 20.9% at studied doses compared with 3.1% with placebo over 72 weeks

Initially approved for diabetes management, semaglutide's weight loss benefits led to further FDA approval for obesity and weight-related conditions

Relative and absolute MACE risk estimates for semaglutide vs placebo To remove the potential impact of the CV effects of active comparators on the analysis, a sensitivity analysis was conducted for semaglutide vs placebo comparator data, thereby excluding active comparator data (Additional file 9: Appendix Figure S3)
