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Nevertheless, insofar as the physiological, postprandial GLP1 release from L cells is concerned, gutderived GLP1 might not reach the CNS at all, but primarily acts locally in a paracrine fashion, activating GLP1 receptors in the vicinity of the intestinal system (Richards et al., 2014)
The results indicated that the oxidative stress and ROS levels induced by LPS and 2,3-cGAMP could be significantly inhibited by C-176 or GLP-1RAs
