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According to the American Diabetes Association's Standards of Medical Care in Diabetes, proper injection technique and systematic site rotation are essential for optimal medication absorption and to prevent lipohypertrophy (thickening of fatty tissue) or lipoatrophy (loss of fatty tissue) at injection sites

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This timeline assumes positive Phase 3 results and a standard FDA review process

Since then, other GLP-1R agonists such as exenatide (Byetta ) and dulaglutide (Trulicity ) have been approve (Holman et al., 2017