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The nutrient depletion risks with GLP-1s mirror findings from bariatric surgery literaturevitamin D, B12, and iron often decline with reduced intake

doi: 10.3390/jcm14134619

11 Both studies helped to highlight that patients on exenatide maintained motor function, whereas the control group had deteriorating motor function over the course of around 1 year, indicating that exenatide has some benefit in delaying the progression of PD

In addition, data indicate that DPP-4 inhibitors also impact immune cell recruitment and reduced macrophage infiltration seemed to be mediated directly via GLP-1-dependent signaling in a rat nephritis model (71)

EMPA-REG vs SURPASS Clinical Trial Data EMPA-REG OUTCOME (n=7,020): This landmark cardiovascular outcomes trial, published in The New England Journal of Medicine, randomized patients with type 2 diabetes and established cardiovascular disease to Jardiance or placebo