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The simple system Dr
Although the pathophysiology of cisplatin-induced cognitive impairment (CICI) has not been fully elucidated, several pathophysiologic mechanisms, including oxidative stress, inflammation, mitochondrial dysfunction, DNA damage, and apoptosis, have been proposed as possible explanations ( Many studies have shown that cisplatin-induced mitochondrial damage in cells leads to oxidative stress and neuronal damage that results in cognitive impairment (CICI) (Taanman, 1999)
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The timeline depends on your starting dose, escalation speed, hydration habits, and how quickly your body's regulatory systems adjust
