retatrutide triple agonist glp-1 gip glucagon phase 2 nejm 2023 is a triple-agonist drug targeting GLP-1, GIP, and receptors to suppress appetite and boost thermogenesis. trials reported 24.2% average weight loss and over 80% liver fat reduction, reversing GLP-1 Receptor Agonists | New
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Saxenda is FDA-approved for chronic weight management, while Ozempic is used for Type 2 diabetes in adults

doi: 10.1056/NEJMoa2403347 35 ArmstrongMJGauntPAithalGPBartonDHullDParkerRet al

"A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults" (PDF)

Low- and middle-income countries demonstrate rapid growth of type 2 diabetes: an analysis based on Global Burden of Disease 19902019 data

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