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[55] Additionally, by blockading FOXO transcription factors and NF-B, the drug modulates SASP and upregulates anti-apoptotic proteins (such as Bcl-2), potentially delaying tissue degeneration and offering anti-aging benefits

Dehydration: Gastrointestinal side effects can also lead to dehydration, contributing to muscle spasms and eye twitching

Instead, the peptide degrades into fragments that are less active

[DOI] [PubMed] [Google Scholar] 22.Perano SJ, Rayner CK, Kritas S et al (2015) Gastric emptying is more rapid in adolescents with type 1 diabetes and impacts on postprandial glycemia

A Kinsey Institute survey of 2,000 adults found 18% of GLP-1 users reported increased sexual desire and 16% reported decreased desire effects running almost equally in both directions