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Description
Compared with placebo or other interventions, GLP-1 receptor agonists use showed an association with an increased risk of overall thyroid disorders (RR 1.28, 95% CI 1.03-1.60)
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For patients considering treatment switches or dose adjustments, this clearance window is clinically relevant
The risk of hypoglycemia with GLP-1/GIP agonists is generally low unless combined with insulin or insulin secretagogues (sulfonylureas), which may require dose adjustment of those medications
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