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Coagulation is a protein that is synthesized in the liver and is the highest coagulation factor with the highest content in plasma

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These results indicate that heterozygous gld-2 and gld-1 mutations are competent for meiotic entry, but haplo-insufficient for the terminal differentiation of spermatocytes in the absence of PUF-8

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Calculations for biopotency and bioavailability (pharmacological availability) are shown below