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Description
GLP-1 receptor agonists should not be used in combination with DPP-4 inhibitors (such as sitagliptin), as both act on the incretin system

Chronic hyperglycemia in diabetes downregulates GIP receptor (GIPR) expression and impairs GIP-mediated insulin secretion [21], rendering high-doses of GIP infusions ineffective [22]

The knowledge saves errors

Patients who combine GLP-1 therapy with expert nutritional guidance, proper protein intake, and ongoing medical supervision consistently achieve the best results
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