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[1] [3] Whilst these mechanisms contribute to improved glycaemic control and weight reduction, they also account for one of the most commonly reported adverse effects: nausea

One of the most surprising findings, according to Gler, was how these drugs [activated] the emotion center and [engaged] the reward mechanisms in the brain. When the researchers gave mice a standard diet, which Gler described as the equivalent of salads for humans, the drugs had no effect

People who have preferences like following a vegan diet may also need special consideration, as they can also be on GLP-1 medications

When to step back down If anxiety symptoms are clearly dose-related, meaning they appear or worsen shortly after a dose increase and do not resolve within two to three weeks, stepping back to the previous dose is a reasonable strategy