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The concentration of bioactive compounds, chiefly the withanolides, can differ significantly based on the plants origin, the parts used, and extraction methods
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This pocket is formed by residues in transmembrane helices 1 (TM1), 2 (TM2), 3 (TM3), and 7 (TM7), along with contributions from extracellular loop 2 (ECL2)
