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349,350 This change suggests that liraglutide not only inhibits inflammation and cartilage degradation but may also promote the synthesis and accumulation of cartilage matrix, thereby helping to protect and repair joint cartilage

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That mechanistic understanding is arguably the most valuable scientific output from this line of research

Without sufficient dietary protein and resistance exercise, this muscle loss may be more pronounced, potentially compromising metabolic health, reducing functional capacity, and diminishing the long-term benefits of weight reduction