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Hyposalivation, a related but distinct condition, refers to objectively reduced salivary flow, typically measured at less than 0.1 mL per minute for unstimulated whole saliva

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Similarly to Ex-4, Liraglutide could reduce signs of apoptosis, most likely through activation of the PKA/beta-catenin pathway [39]

Efinopegdutide is another GLP-1R and GCGR dual agonist currently under clinical investigation, which is being explored in studies for patients with obesity, type 2 diabetes (T2D), and metabolically associated fatty liver disease/multiple acyl-CoA dehydrogenase deficiency syndrome (MASLD/MASH)