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Figure 3 Conclusions DPP-4 inhibitors are important oral antidiabetic agents that are placed as second-line therapy after metformin failure as insulinotropic agents that have no intrinsic hypoglycaemia risk and are body weight neutral

You are encouraged to report negative side effects of prescription drugs to the FDA

This gradual titration is designed to help you avoid the food noise and cravings that often derail weight loss without overwhelming your system

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While timing alone is unlikely to be the sole cause, it is one piece of the optimization puzzle that is easy to adjust and test