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Vitamin D is the most commonly deficient nutrient in GLP-1 users, with 13.6% developing clinical deficiency within 12 months

Standard compounding pharmacies are not required to register as outsourcing facilities but must comply with relevant sections of the Federal Food, Drug, and Cosmetic Act

For patients with pre-existing diabetic retinopathy, ophthalmologic follow-up is recommended, particularly during periods of rapid glycemic improvement

For clinicians and patients, the takeaway is clear: GLP-1RAs remain safe and effective for diabetes and obesity, with possible added benefits for cancer prevention

As part of their agreements with CMS, the manufacturers must demonstrate how these lifestyle support programs will meet the program requirements, including encouraging healthy eating and increasing physical activity, supporting medication adherence, ensuring engagement with the program on a regular basis, and ensuring availability of this program to all patients receiving these medications, either online or offline for those who have limited digital access