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The use of GLP-1s has been found to reduce food cravings for high-fat foods, sugary foods and alcohol

Immunocytochemistry for detection of GLP-1 Cultures of mouse intestinal cells were fixed for 10 min at room temperature in PBS containing 4% paraformaldehyde, and were then permeabilized by incubation for 10 min in PBS containing 0.25% Triton X-100

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Second, GLP-1 affects the gut microbiome, intestinal permeability, and gut-derived inflammation, none of which require weight loss