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In these trials, participants treated with Wegovy experienced substantial weight loss, making it a much-needed addition to the arsenal of obesity treatments

Peptide YY (PYY) PYY is a 36 amino acid peptide that is cleaved by DPP-4 to generate PYY(336), a peptide that inhibits food intake by activating the Y2 receptor (Y2R)

Key Background Novo Nordisk was the first major pharmaceutical company to bring a GLP-1 to market with Wegovy in 2021

Fifteen studies (836 participants) were pooled for the analysis of post-interventional fasting insulin levels (Electronic Supplementary Fig

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