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doi: 10.1111/dom.14710

Indeed, activation of GLP-1R in different brain regions reduces food intake 6 and we clearly show that the OB is among these brain areas, with the demonstration that GLP-1-driven OB output activity also modulates food intake in a DIO model

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A inibio do glucagon pela semaglutida contribui para a reduo da glicose sangunea em pacientes com DM2

9 Patients with T2DM receive exenatide by subcutaneous injection, and circulating exenatide produces a blood glucose-lowering effect since it directly activates the GLP-1R