first glp 1 drug Evolution of GLP‐1 Receptor Agonists for Diabetes Treatment New GLP-1 Guidelines for Type
Description
Over time, the body develops some tolerance to the gastric slowing effect, so their gastric emptying delay is less acute (and thus they have milder postprandial effect relative to short-acting ones) ( [112] ) ( [113] )

Guevara, L

Mechanisms underlying GI side effects

New combinations, such as GLP-1 agents paired with a mimic of the hormone amylin (which helps with fullness and lowering blood sugars), are showing significant promise and will be powerful tools in the toolbox

A better understanding of the biological underpinnings of AIWG could inform targeted and potentially more fruitful treatments
