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These data suggest that GLP-1R agonism attenuates atherosclerosis formation and vascular immune cell activation most likely by reducing systemic inflammation independently of changes in lipid and glucose metabolism

In the United States, the monthly cost of GLP-1 medication can range from approximately $900 to over $1,300 without insurance coverage

Starting dosage often begins low and is increased gradually to improve tolerability (reduce GI sideeffects) and let the body adjust

Uninsured patients represent one of the fastest-growing populations seeking weight loss medication, driven by rising obesity rates and limited employer-sponsored coverage options

Although publication bias should always be considered (Jennings & Van Horn, 2012), neuroimaging studies are likely more susceptible to confirmation bias due to high analytical flexibility (Mller et al., 2018)