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Leptin resistance is the inability of obese individuals or diet-induced obese models to respond to exogenous and endogenous leptin

doi: 10.1016/J.APPET.2022.106022

Gastric sleeve surgery (also known as sleeve gastrectomy or vertical sleeve gastrectomy): A surgeon removes about 80 percent of the stomach, leaving behind a sleeve or tube made up of the remaining 20 percent

For those experiencing constipation, bulk-forming laxatives such as ispaghula husk (psyllium) or methylcellulose may be recommended as first-line options after consulting a pharmacist or GP

These services combine medication management with behavioral support, creating comprehensive approaches to weight and metabolic health